Venerdì 17 settembre
Newcastle-Leeds 1-1 (13′ Raphinha, 44′ Saint-Maximin)
Sabato 18 settembre
Wolverhampton-Brentford 0-2 (28′ rig. Toney, 34′ Mbeumo)
Norwich-Watford 1-2 (17′ Dennis, 34′ Pukki, 63′, 83′ Sarr)
Burnley-Arsenal 0-1 (30′ Odegaard)
Manchester City-Southampton 0-0
Liverpool-Crystal Palace 3-0 (43′ Mané, 78′ Salah, 89′ Keita)
Aston Villa-Everton 3-0 (66′ Cash, 69′ aut. Digne, 75′ Bailey)
Domenica 19 settembre
Brighton-Leicester 2-1 (35′ rig. Maupay, 50′ Welbeck, 61′ Vardy)
West Ham-Manchester United 1-2 (30′ Benrahma, 35′ Ronaldo, 89′ Lingard)
Tottenham-Chelsea 0-3 (49′ T. Silva, 57′ Kanté, 90’+2 Rudiger)